FDA approves Jardiance for treatment of type 2 diabetes

The FDA has approved jardiance for the treatment of type 2 diabetes, it was announced today. Jardiance, which is also known as empagliflozin, is used alongside exercise and a balanced diet to help improve glycemic control in adults with type 2 diabetes.

Jardiance works by preventing the re-absorption of blood sugar by the kidneys and increases glucose excretion. It also lowers the blood sugars of patients with type 2 diabetes when their glucose levels are elevated.

Commenting in a press release, Curtis J. Rosebraugh, M.D., M.P.H., director of the Office of Drug Evaluation II in the FDA’s Center for Drug Evaluation and Research, said:

"Jardiance provides an additional treatment option for the care of patients with type 2 diabetes."
“It can be used alone or added to existing treatment regimens to control blood sugar levels in the overall management of diabetes.”

Nearly 5,000 patients with type 2 diabetes took part in the trial and it was found that the drug effectively improved the AIc levels when compared to a placebo.

Studies have been conducted into using jardiance as a standalone treatment for type 2 diabetes and it has also been used in conjunction with other forms of drugs such as metformin.

However, the drug can't be taken by patients with type 1 diabetes, patients on kidney dialysis, end stage renal disease, or by patients with high levels of ketones in their blood or urine.

The original press release can be found here.

American Association of Diabetes Educators offers Travel Tips

Holiday season will soon be in full swing so the American Association of Diabetes Educators have issued a press release detailing some travel tips.

Newswise — AAA estimates 36.1 million people will travel this Memorial Day weekend. If diabetes is your constant companion, that doesn’t mean you can’t enjoy traveling, whether traversing America in an RV or flying to the far reaches of the globe. Ensuring you stay healthy and keep your glucose levels on an even keel does require a little bit of organization and planning ahead, though.

The American Association of Diabetes Educators suggests a plan of attack for ensuring your next travel adventure is safe and successful:

- Over-pack your medications – Gone for a week? Pack two weeks’ worth of your diabetes medications in case of travel delays or misplaced supplies (insulin, syringes, testing strips, extra batteries for your pump, a first-aid kit, glucagon emergency kit, etc.). If you use a pump, ask the company if you can bring a backup in case yours fails. Have a prescription from your doctor for insulin or oral medication in case of an emergency.

- Protect your supplies – Keep your medications and supplies close at hand and don’t put them in checked luggage or in the trunk, where they can be exposed to harmful extreme temperatures (too hot or too cold). If you’re flying, keep them in the original packaging (so no one questions they’re yours) in a bag separate from your toiletries, as requested by the Transportation Security Administration (TSA), which manages airport security. Don’t worry, the TSA allows you to go over the 3.4 liquid-ounce carry-on limit for diabetes medications and supplies.

- Identify yourself – Wear your medical bracelet or necklace that notes you have diabetes and take insulin (if you do). Bring a doctor’s note that explains you have diabetes and lists your medications, as well as a prescription in case you need more. Carry a health card that includes your emergency contact and doctor’s name and phone number. Learn how to say “I have diabetes,” “sugar,” and “orange juice, please” in the language of the country you are visiting.

- Carry snacks and low blood sugar treatment – Low blood sugar (hypoglycemia) can strike any time and food access during travel is unpredictable, so be sure to bring plenty of snacks such as peanut butter crackers, granola bars and trail mix as well as glucose tablets or gel.

- Simplify flying – Tell the TSA folks that you have diabetes (they’re used to accommodating people with health issues). Visit http://www.tsa.gov/traveler-information/passengers-diabetes before your trip to learn about current screening policies. If you plan to inject insulin while flying, be forewarned – the pressurized air can make it more challenging to draw up your insulin, if using a vial and syringe, so be extra careful not to inject air into the bottle.

- Test often – New foods, increased activity and different time zones can throw your glucose levels out of whack, so be sure to test frequently, including before and after meals. If you take insulin, keeping your levels steady can be tricky when changing time zones, so make a plan to adjust your schedule for injecting. Before your trip, see a diabetes educator, who can help you with this challenging process.

- Favor your feet – Wear comfortable well-fitting shoes and socks at all times – never go barefoot. Check your feet frequently, especially after a hike or long walk. Feet and ankles often swell during flights so consider wearing light knee-high compression stockings (20-30 mm Hg) or bring thinner socks to change into if your feet swell. Wear a shoe that can be loosened if that occurs. Pointing and flexing your ankles during a flight can improve blood flow in your calf muscles and decrease swelling as well as lower the risk of blood clots.

- Prepare for a health emergency – If you need medical treatment, ask your hotel to recommend a local doctor who treats diabetes. Prior to an overseas trip, get a list of local English-speaking doctors through the International Association for Medical Assistance to Travelers athttp://www.iamat.org/.

The secret to any successful trip is to take plenty of time and plan far in advance of your departure – and that goes double when you have diabetes. For more information about how a diabetes educator can help you plan your next trip, visit http://www.diabeteseducator.org/.

Sources: Centers for Disease Control and Prevention (CDC), American Diabetes Association and Joslin Diabetes Clinic

The original press release can be viewed at:

http://www.newswise.com/articles/view/618258/?sc=dwhn