A team of researchers from the Washington University School of Medicine have used a natural compound to restore normal glucose metabolism in mice, the researchers say that it could mean that eventually patients with type 2 diabetes would be able to take the compound in the same way that they would a vitamin tablet and it could be used as a means to prevent type 2 diabetes.
The compound used is an enzyme called nicotinamide mononucleotide (NMH), commenting in a press release, Shin-ichiro Imai, MD, PhD, associate professor of developmental biology, said:
“After giving NMN, glucose tolerance goes completely back to normal in female diabetic mice."
“In males, we see a milder effect compared to females, but we still see an effect. These are really remarkable results. NMH improves diabetic symptoms, at least in mice.”
The trials have so far been carried out in mice and it was found that after having NMH administered, glucose tolerance returned to normal in the female mice and improved in the male mice.
The researchers are hopeful that the NMH could one day used as a treatment for humans and they hope to do a human trial at some point.
The compound used is an enzyme called nicotinamide mononucleotide (NMH), commenting in a press release, Shin-ichiro Imai, MD, PhD, associate professor of developmental biology, said:
“After giving NMN, glucose tolerance goes completely back to normal in female diabetic mice."
“In males, we see a milder effect compared to females, but we still see an effect. These are really remarkable results. NMH improves diabetic symptoms, at least in mice.”
The trials have so far been carried out in mice and it was found that after having NMH administered, glucose tolerance returned to normal in the female mice and improved in the male mice.
The researchers are hopeful that the NMH could one day used as a treatment for humans and they hope to do a human trial at some point.
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